IMPROVING QUALITY OF LIFE FOR WOMEN WITH GENETIC-RELATED INFERTILITY

Background: Infertility treatments significantly impact the quality of life for women, with poor psychological well-being often leading to higher rates of treatment discontinuation. Specific Background: In vitro fertilization (IVF) is a common intervention for genetically infertile women, yet its effects on quality of life remain underexplored, particularly using comprehensive tools like the Fertility Quality of Life Questionnaire (FERTIQOL). Knowledge Gap: Previous studies have not thoroughly assessed the impact of IVF on quality of life using FERTIQOL among genetically infertile women in specific geographic locations, such as Iraq. Aims: This study aims to evaluate the FERTIQOL among genetically infertile women undergoing IVF to determine its impact on their quality of life. Results: A total of 75 genetically infertile women, aged 20-45 years, were recruited from Baghdad hospitals between April 6, 2023, and October 10, 2024. The study found a 64% prevalence of primary infertility and a 36% prevalence of secondary infertility. Post-IVF complications occurred in 25.33% of cases, and pregnancy loss was reported in 32% of patients. Hormonal levels were recorded as follows: FSH 6.58 ± 0.05 IU/L, LH 6.52 ± 0.61 IU/L, estradiol 161.92 ± 6.18 pmol/L, and progesterone 0.89 ± 0.48 nmol/L. The FERTIQOL scores revealed a mean tolerability score of 76.55 ± 13.20, a treatment FertiQoL score of 67.91 ± 10.83, a relational score of 60.02 ± 8.74, and a Mind/Body score of 68.78 ± 16.59. Novelty: This study is among the first to assess the impact of IVF on quality of life in genetically infertile women using FERTIQOL in an Iraqi setting. Implications: The findings highlight the significant role of IVF in managing genetic infertility and its profound impact on patients' quality of life, underscoring the need for comprehensive support systems during treatment.

Kata Kunci