Synthesis of Some New Hydroquinone Compounds Derived From 2-Amino Benzothiazole and Study Their Biological Activity

Substituted 2-amino benzothiazoles (w1-W3) were produced in the current study via a reaction involving potassium thiocyanate and aniline that had been substituted with the assistance of a broom. Schiff bases are produced by reacting substituted 2-amino benzothiazoles (w4-W6). The products of the reaction between anthranilic acid and Schiff base were hydroquinone compounds (w7-9). Each new compound was identified using spectral (IR, 1H-NMR) and physical techniques. The antibacterial activity against gram-positive and gram-negative microorganisms was evaluated vitro using the disc diffusion assay method. The minimum inhibitory concentration (MIC) was ascertained using standard drugs as a reference. The findings indicated that hydroquinone derivatives exhibited superior activity against the proliferation of gram-positive and germ-negative bacteria compared to the drug.