Correlation Analysis of Immunological Markers in Pediatric Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) in children represents a complex autoimmune disorder with diverse immunopathogenic mechanisms. Early recognition of immune dysregulation is essential for optimizing treatment strategies and predicting disease outcomes [1]. Immunological markers, including acute-phase proteins, cytokines, and complement components, provide valuable insights into the underlying mechanisms of inflammation [2]. Studying their interactions can reveal key pathogenic pathways and potential therapeutic targets [3]. In pediatric patients, where immune responses may differ from adults, such data are particularly critical for clinical decision-making.