Publication Details
Abstract
Background: According to recent beliefs, certain immunological variations discovered in patients may be related to alopecia, particularly the alopecia areata kind.
Objective: The current study's objective is to detect, evaluate, and estimate certain hematological parameters in alopecia areata (AA).
Material and methods: A retrospective analysis was done between July 2022 and February 2023. A total of 120 alopecia patients from AL-Qadisiyah hospitals, private clinics, and AL-Karamah private hospitals were examined. Blood was drawn from the patients, spun apart to separate the serum, and then processed using immunological methods.
Results: Out of 120 samples, the results showed that 80 (66.66%) had alopecia areata, whereas 40 (33.22%) had the other forms (alopecia universalis and alopecia totalis). From the findings, immunological alterations in alopecia areata patients were discovered, The results of CD4 showed that the patients with alopecia areata was the highest (n=80) 4.06 ± 0.93 compared with control (n=60) 3.18 ± 0.65, results of CD8 showed that the patients with alopecia areata was the highest (n=80)323.7± 127.3 compared with control group(n=60) 159.8±62.1 .
Conclusion: By revealing the existence of particular immunological components in patients who acquire alopecia, the study laid the groundwork for a wider and more in-depth investigation of immunological abnormalities in people with alopecia areata or totalis.