Primary Multiple Skin Melanomas

Primary multiple skin melanomas represent a particular interest in modern oncology. Despite numerous studies on this topic in the global literature, most of them present isolated observations. The frequency of primary multiple melanomas in relation to all skin melanomas ranges from 0.54% to 4% according to various authors (American Cancer Society, 2021). In men, the risk of developing primary multiple melanoma is three times higher than in women, especially at a young age (Robert, C., Thomas, L., Bondarenko, I., ODay, S., Weber, J., Garbe, C., Lebbe, C., Baurain, J.F., Testori, A., Grob, J.J., Davidson, N., Richards, J., Maio, M., Hauschild, A., Miller, W.H.Jr., Gascon, P., Lotem, M., Harmankaya, K., Ibrahim, R., Francis, S., Chen, T.T., Humphrey, R., Hoos, A., Volchok, J.D., 2011).