Immunological Aspects of the Pathogenesis of Gingivitis and Periodontitis

The participation of the immune system in the pathogenesis of inflammatory periodontal diseases is evidenced by numerous studies [36,38,106,118,151,155,158,168,178]. In patients with gingivitis and periodontitis , a violation of the immune status indicators was revealed - a change in the phagocytic activity of neutrophils, which is confirmed by a decrease in the phagocytic number to the phagocytic index [17,50,104,115]; an increase in the activity of enzymatic oxygen-radical reactions of neutrophils [56,100,106,143,167].