COVID 19 Severely Disrupts Blood Markers and Renal Function

Since the emergence of COVID-19 in Wuhan, extensive research has explored its immediate and long-term effects. This study investigated the relationship between COVID-19 and blood disorders, liver proteins, and biochemical factors. We analyzed 150 samples divided into two groups: 75 COVID-19 patients and 75 healthy, recovered individuals aged 25-75 years. The study examined various hematological and biochemical markers, including WBC, lymphocytes, platelet count, NLR, RBC, CRP, BUN, creatinine, D-dimer, and ferritin. Significant differences were found in hemoglobin levels, WBC count, RBC, blood urea, and serum creatinine, with COVID-19 patients showing increased levels of these markers except for hemoglobin, which decreased. The results indicate that COVID-19 adversely affects hematological markers, renal function, and induces abnormal immune responses. Moreover, the severity of illness is positively associated with blood hemolysis and D-dimer levels, leading to hyperglycemia and pancreatic effects by inhibiting insulin synthesis. These findings underscore the impact of COVID-19 on blood parameters and organ function.