Publication Details
Abstract
Non-alcoholic fatty liver disease (NAFLD) is an increasing worldwide health issue marked by fat buildup in more than 5% of liver cells. This disease is primarily caused by the obesity epidemic and affects approximately 25% of the world's population. NAFLD might lead to various degrees of cirrhosis in a persistent liver illness. Lastly, NAFLD could result in the development of cancer of the liver. This review aims to describe and estimate erythropoietin levels and lipid levels (TG, TC, HDL, LDL, V-LDL) and some trace elements (Selenium (Se), Iron(Fe)) in patients with fatty liver disease. Serum erythropoietin and lipid levels (triglycerides (TG), cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), very low-density lipoprotein (V-LDL)) and selenium and iron levels were determined in 96 volunteers from men and women: 73 patients and 23 healthy control group. Patients were diagnosed by an internist medicine specialist. Inclusion Criteria: The cases included in this study are patients with non-alcoholic fatty liver disease, diabetes, and hypertension. Exclusion Criteria: The cases excluded from this study are patients with alcoholic fatty liver disease or fatty liver with other diseases such as heart and kidney disease. An important increase in focus of erythropoietin in fatty liver in the DM also fatty liver in the DM and HTN cohorts compared to fatty liver and controls groups (p≤0.05), An important increase in focus of TC in patients cohorts compared in the controls groups (p≤0.05), An important increase in focus of TG and VLDL in patients groups compared to controls groups (p≤0.05), An important increase in focus of LDL in patients groups compared to controls groups (p≤0.05),and An important decrease in focus of HDL in patients groups compared to controls groups (p≤0.05). An important increase in focus of Se in patients groups compared to controls groups (p≤0.05). An important increase in focus of Fe in patients groups compared to controls groups (p≤0.05). The study indicated that there was an increase in the levels of erythropoietin, as well as an increase in the level of (TG, TC, LDL, V-LDL), Se, Fe, and a decrease in the level of (HDL) in patient’s fatty liver.