Publication Details
Abstract
This study was carried out from January to March 2024, aimed at assessing the impact of bee glue extracts (aquatic and ethanolic) on the oxidant-antioxidant balance by estimating the concentration of certain antioxidants and their indicators such as glutathione (GSH) and malondialdehyde (MDA), as well as assessing their impact on kidney functions by estimating the concentration of urea , creatinine, Blood urea nitrogen (BUN),BUN/Creatinine ratio and creatinine clearance (CrCl) among male rats exposed to hydrogen peroxide-induced oxidation stress. The results showed that treatment with bee glue extracts led to an increase in GSH , BUN/Creatinine ratio and CrCl levels in serum and a decrease in MDA, urea, creatinine and BUN levels compared to the H2O2 group. The study results indicate that both aqueous and alcoholic extracts of bee glue have a preventive role against oxidative damage caused by stress. This is achieved by improving the levels of GSH , BUN/Creatinine ratio and CrCl levels and reducing the level of lipid peroxidation (MDA). Additionally, the kidney function is enhanced by reducing the levels of urea , creatinine and BUN in rats treated with H2O2.