Synthesis, Charactarizit and Evaluation of Bacterial Efficacy and Study of Molecular Substrates of Cobalt (II) Complex [Co (2-(benzo[d]thiazol-2-yloxy) acetohydrazide) (H2O) (Cl2)]

Due to the importance of medical and biological cobalt complexes, in this research, a new complex of cobalt complexes was prepared [Co (2-(benzo[d]thiazol-2-yloxy)acetohydrazide)(H2O)(Cl2)] using 2-(benzo[d]thiazol-2-yloxy)acetohydrazide as a basic alkand.the lycand was prepared from the reaction of the ester with aqueous hydrazine. , using physical techniques (color, melting point, Rf ) and spectral methods (FT-IR infrared spectrum, carbon-Proton NMR spectrum 1H-NMR , 13C-NMR, SEM & XRD) the correctness of the compositions of the prepared compounds was confirmed , and then the bioeffectiveness of the series of compounds was studied on two types of Gram-positive and Gram-negative bacteria (Staphylococcus aureus and Escherichia coli), And the study of the molecular Docking of the complex and the ligand on Pseudomonas aeruginosa bacteria and the calculation of the binding energy and RMSD values.