Synthesis and Characterization of Some New Imine Graphene Derivatives and Evaluation of Their Biological Activity

This study aimed to synthesize and characterize new imine graphene derivatives and evaluate their biological activity. Various nanoderivatives of graphene oxide were prepared and functionalized with symmetrical triazoles and amines through reactions involving oxidizing and acidic agents. The synthesis process included chemical exfoliation to create graphene oxide (GO), reduction of GO to reduced graphene oxide (RGO), and further functionalization with thiocarbohydrazide and triazoles. The resulting compounds were characterized using FT-IR, XRD, and SEM. Biological activity was tested against gram-positive Staphylococcus epidermidis and gram-negative Klebsiella pneumoniae bacteria. The synthesized compounds showed significant antibacterial activity, demonstrating their potential as antimicrobial agents.