Publication Details
Abstract
This study aimed to assess the changes in biochemical markers in type 2 diabetic patients after receiving the Pfizer COVID-19 vaccine. The research focused on measuring cardiac biochemical markers, specifically myoglobin and lipid profiles, as well as routine kidney function tests (blood urea and serum creatinine) following the second dose of the Pfizer vaccine. Myoglobin levels were estimated using an ELISA kit, while lipid profiles and renal function were determined using the Cobas analyzer. The results indicated higher myoglobin levels in both vaccinated and non-vaccinated diabetic groups compared to healthy controls. There were significant differences in lipid profiles between diabetic groups, although no significant differences were found between vaccinated and non-vaccinated groups. HDL levels were lower in both diabetic groups compared to healthy controls. The study found no significant adverse effects of the Pfizer vaccine on kidney function tests, with T2DM patients showing higher levels of myoglobin and lipid profiles but no significant difference between vaccinated and non-vaccinated individuals.