Publication Details
Abstract
The Coronavirus Disease 2019 (COVID-19) can cause fatal outcome. A number of factors, including blood glucose levels, can impact how this disease progresses. One of the test results that is utilized to assess the prognosis of COVID-19 patients is D dimer. The aim of this study is to ascertain how blood sugar levels affect D-dimer levels in PKU Muhammadiyah Gamping Hospital COVID-19 inpatients. This research is aquantitative analytical observational study with a cross sectional design. The number of samples in this study was 373 samples, consisting of 213 samples of COVID-19 patients with blood glucose <200 mg/dl and 160 samples of COVID-19 patients with blood glucose >200 mg/dL. The sample was obtained using a simple random sampling method. Analysis was applied to determine the correlation between blood sugar levels and D-dimer levels from the two sample groups. This study also measured the D-dimer cut-off point value which was assessed using the ROC curve. Results: No significant correlation was found between blood sugar levels and D dimer levels in COVID-19 patients hospitalized at PKU Muhammadiyah Gamping Hospital (p>0.05).The cut-off pointvalue of D-dimer in diabetes patients is 1,505 mg/dL with sensitivity of 62,7% and specificity of 63,8% and the risk of death is 2,2 greater in patients with D-dimer levels >1,505mg/dL (RR: 2,217; 95% CI: 1,499- 3,278). Conclusion: Blood sugar and D-dimer levels did not significantly correlate in COVID-19 inpatients. The risk of death in patients with D-dimer levels >1.505 mg/dL was 2.2.