Urtica Dioica, Melissa Officinalis Ba Leonurus Cardiaca, Optimization of the Process of Extraction of Flavonoids from Collective RAW Materials with a Sedative Effect Formed from the Surface Part of Plants

Factors influencing the extraction process of flavonoids with 70% ethyl alcohol from medicinal nettle, a mixture of medicinal ratios, were studied by mathematical planning using the Box-Wilson method, and the following optimal conditions were selected: Process time: 6 hours; degree of grinding of raw materials: 6 mm; process temperature: 30 °C; raw material and solvent ratio: 1:4.5. By researching the dynamics of the extraction process, it was determined that extraction should be done five times. It was found that these conditions allow to extract 95.25% of flavonoids compared to the storage in raw materials.