Comparative Analysis of Three-Dimensional Conformal Radiation Therapy (3D-CRT) and Volumetric Modulated Arc Therapy (VMAT) in Prostate Cancer: Accuracy, Duration, Side Effects, and Costs

This study offers a comparative analysis of 3D Conformal Radiation Therapy (3D-CRT) and Volumetric Modulated Arc Therapy (VMAT) in prostate cancer treatment, focusing on treatment accuracy, duration, side effects, and costs. While VMAT demonstrates greater precision by delivering targeted radiation with minimal impact on surrounding tissues, 3D-CRT has been a widely used option due to its lower costs. However, VMAT's faster treatment sessions, reduced side effects, and potential long-term cost savings present significant advantages. This study addresses the knowledge gap regarding the trade-offs between the two methods by analyzing clinical outcomes and economic impacts. The findings suggest that although VMAT requires higher initial investment, it enhances treatment efficiency and patient outcomes, potentially justifying the costs. The study highlights VMAT’s potential to reduce long-term healthcare burdens associated with prostate cancer treatment.