Publication Details
Issue: Vol 5, No 4 (2024)
Pages: 996-1001
ISSN: 2660-4159

Abstract

Pseudomonas aeruginosa is a Gram-negative pathogen known for causing infections in hospitalized patients, particularly due to its multidrug resistance mechanisms, which significantly increase morbidity and mortality. The growing prevalence of multidrug-resistant strains has severely limited treatment options, highlighting the urgent need for novel therapeutic approaches. This study aimed to evaluate the antibiotic susceptibility of P. aeruginosa isolates from wound infections in patients at Hussain Teaching Hospital, Nasiriyah, between February and September 2024. Out of 100 wound samples, 14 P. aeruginosa isolates were identified using biochemical, morphological, and culture analyses. Antibiotic susceptibility testing revealed that most isolates showed high resistance to trimethoprim/sulfamethoxazole and amoxicillin, while imipenem was the most effective antimicrobial agent. These findings underscore the importance of continuous monitoring of antibiotic resistance patterns and the need for alternative treatment strategies to combat drug-resistant infections.

Keywords
Antimicrobial resistance Wound infection Pseudomonas aeruginosa