Publication Details
Abstract
In this paper, a detailed chemical analysis of the hydrodistillate of the above-ground part of the plant Melissa officinalis L. using gas chromatography with mass spectrometry (GC-MS) was carried out. The study showed that the hydrodistillate obtained from the above-ground part of Melissa officinalis contains a rich complex of bioactive compounds including terpenes, flavonoids, phenolic acids and other volatile substances. The major components identified include 1,4-Dioxaspiro[4.5]decane-7-butanoic acid, 6-methyl-, 2-(methylsulfonyloxy)ethyl ester (12.59%) and 2-octadeca-9,12-dienoxyethanol (8.59%). Analysis of the hydrodistillate composition also revealed the presence of compounds such as Dipalmitin, Ethyliso-allocholate and Glycine, N-[(3α,5β)-24-oxo-3-[(trimethylsilyl)oxy]cholan-24-yl]-, methyl ester. These data are important for standardisation and quality control of melissa-based phytopreparations and for the development of new therapeutic and cosmetic products