Publication Details
Abstract
The present investigation was conducted on type 1 diabetes individuals infected with the Toxoplasma gondii parasite. The potential association between toxoplasmosis infection and type 1 diabetes (1DM) remains under investigation. This study aims to examine the role of interleukin-2 and interleukin-17 in the immune response to parasites. A total of 160 serum samples were obtained from Thi-Qar hospitals and private laboratories, categorised into four groups: 40 samples from type 1 diabetes patients infected with toxoplasmosis, 40 samples from type 1 diabetic patients only, 40 samples from patients with toxoplasmosis only, and 40 samples from the control group. The study results indicated that the serum concentration of IL-2 was highest in the type 1 diabetes group infected with toxoplasmosis, followed by the type 1 diabetic group alone, then the toxoplasmosis-infected group, with the control group exhibiting the lowest concentration. The IL-17 serum levels were elevated in the toxoplasmosis-infected group, followed by the type 1 diabetes group infected with toxoplasmosis, while the control group had the lowest concentration.