Publication Details
Issue: Vol 6, No 1 (2025)
Pages: 398-404
ISSN: 2660-4159

Abstract

This study included 100 kidney failure patients. Five ml of blood was collected from each patient, the plasma was separated, and then the plasma samples were stored until DNA extraction was performed. Molecular detection of Cytomegalovirus (CMV) was done by polymerase chain reaction (PCR). Urine samples were also obtained for bacterial species. The results of the PCR technique revealed that 8 patients were infected with the CMV at a rate of 8 %, with 5 infections in males and 3 infections in females, with a rate of 8.9% and 6.8% respectively. Regarding the age group, the highest incidence of the virus was in 21-30 age group in males and the 41-50 age group in females. The results of bacterial detection show that E. coli cause the highest rate of urinary tract infections in hemodialysis patients infected with the CMV at 100%, followed by Klebsiella pneumonia at 60%. We conclude that patients receiving end-stage renal dialysis may be more susceptible to CMV replication while they get chronic hemodialysis.

Keywords
Cytomegalovirus Kidney failure Real-time PCR UTI