Publication Details
Abstract
Based on our own research and recent literature data, we have studied risk factors influencing the formation and progression of nephropathies (hereditary, teratogenic, external environmental). With timely detection and adherence to simple preventive measures (diet, fluid regimen, microclimate, elimination of infectious, toxic, allergic effects, and dysmetabolism correction), they do not lead to complications (interstitial nephritis (IN), urolithiasis (UTI), secondary dysmetabolism (SD), secondary pyelonephritis). External environmental factors contributing to the manifestation of pathology in children with metabolic disorders include seasonal climatic fluctuations - adaptation to low and high temperatures, dietary errors, emotional and physical overloads, membranopathies, and intercurrent diseases. It has been established that the presence of latent diathesis in a child from a family with a predisposition to certain diseases (ancestry, hereditary burden index) is determined using biochemical, immunological, and functional studies. A scheme for the preventive prevention and metaphylaxis of nephropathies in uric acid diathesis has been developed.