Publication Details
Abstract
The growing interest in natural compounds with medicinal potential has prompted researchers to explore the bioactive components of A. graveolens (Greater Celandine). The aim of this study is to evaluate the antioxidant activity of flavonoid extracts and the alcoholic extract of A. graveolens, in addition to determining the chemical composition of the alcoholic extract using GC-MS analysis. The results of GC-MS analysis showed the presence of a variety of chemical compounds in the alcoholic extract of A. graveolens, including alkanes, alcohols, organic acids, and silicon compounds. This chemical diversity indicates the possibility of biologically active compounds in the extract. The anti-oxidant activity study showed that both extracts (flavonoid and ethyl alcohol) have significant antioxidant activity, as their activity is similar to that of vitamin C, which is a well-known antioxidant. The A. graveolens alcoholic extract showed the highest percentage at the lowest concentration (200 μg/ml), which indicates that the antioxidant activity is higher at low concentrations. These results indicate that Nabat al-Shabat contains biologically active compounds with antioxidant properties. These compounds play a role in protecting cells from oxidative damage caused by free radicals, which are associated with the development of many chronic diseases. These results encourage further research to determine the specific chemical compounds responsible for the antioxidant activity in the nightshade, and to evaluate its activity and safety in various applications.