Publication Details
Abstract
vermicularis (pinworm) is the most prevalent helminth infection in middle- and high-income nations, especially in school-age children. E. vermicularis is found all across the world and is not linked to any specific racial, cultural, or social background. To investigate the role of IL5 in immunity against E. vermicularis infection through measuring serum level among infected children and healthy control group. Between August 2024 and January 2025, 45 children—24 boys and 21 girls—from patients who visited AL-Zahraa Teaching Hospital in AL-Najaf province participated in the current study. For hematological parameters and IL5 measurement by ELISA, 5 ml of samples were drawn from the veins of the patients and the control group. The information was entered using SPSS version 22.0. In this study, the relationship between the two variables was analyzed and assessed using the chi-square test. The t-test was used to analyze the differences in serum parameters between the two groups. The threshold for statistical significance was set at P < 0.05. Infected children had a significantly lower hemoglobin level than the controls (12.06 vs. 13.46) respectively. Therefore, the mean of hemoglobin was highly significant, as (P= <0.001), while, white blood cells and Eosinophils' showed a highly significant increase (P= <0.001), in patients when compared with control. Interleukin 5 was assessed for both patient and control groups and the mean showed there were a highly significant increase in infected children when compared with control (P=0.0001).