Application of Specialized Amino Acid Solutions in Intensive Care Therapy of Sepsis

Sepsis remains one of the leading causes of mortality in intensive care units. Metabolic disorders, protein catabolism, and deficiency of certain amino acids worsen the course of the disease. In recent years, the role of specialized amino acid solutions aimed at correcting metabolic disturbances and modulating the immune response has been actively studied. The most important amino acids are glutamine, arginine, cysteine, ornithine, and taurine, which have pronounced antioxidant, immunomodulatory, and endothelioprotective properties. This review summarizes current data on the use of amino acid solutions in intensive care therapy of sepsis, their impact on outcomes, and perspectives for further use.