Publication Details
Abstract
The problem of selection the type of mesh implant is actual in herniology for today. The work is dedicated to clinical and experimental testing of the new domestically made mesh implant with complex emulsion covering Niprocel" taking into account the developed operations with using it – corrective allohernioplasty. A scientific team of Health Sciences, The Republic specialized scientific and practical medical center of surgery named after academician V.Vakhidov and Khorezm Regional Multidisciplinary Medical Center created a new composite cover for mesh prosthesis. The clinical trials involved 239 participants with postoperative ventral hernias. All patients were divided into 2 groups: the main group (n=97) was made up of those who underwent uneven allohernioplasty with a new type domestic mesh prosthesis. The control group consisted of 142 patients who underwent the allohernioplasty using conventional prostheses (Esfil, Prolen). The first clinical trials of the original domestic polypropylene endoprosthesis with a complex "Niprocel" membrane demonstrated full correlation of experimental and practical data. Comparative evaluation of the clinical efficacy of allohernioplasty with the use of the developed mesh prosthesis indicated that bioinertion, combined with hemostatic-lymphostatic effects and a reparative potential of the created composite coating, decreases probability (13.1%) development of local reactive changes against an implant which ensured higher indices in life quality after surgery and also more frequency good results.