Publication Details
Abstract
Urolithiasis (kidney and urinary tract stone disease) in premature children is a serious pediatric problem, and its early detection and prediction are of great importance in clinical practice. This article analyzes methods for determining the risk of developing urolithiasis based on urine metabolic indicators (calcium, oxalate, citrate and their ratios). The aim is to predict the risk of urolithiasis in premature children based on the metabolic profile and to identify clinically applicable diagnostic indicators. The analysis shows that hypercalciuria, hyperoxaluria and hypocitraturia are the main risk factors for the development of stone disease in children. Regular monitoring of urine metabolic indicators allows to identify the early stages of urolithiasis and determine preventive strategies. Also, in combination with metabolic indicators, clinical history and family predisposition data increase the accuracy of the prognosis.