Publication Details
Abstract
Background; Hashimoto thyroiditis is an autoimmune illness that destroys thyroid cells through cell and antibody-mediated immunological mechanisms. In developed countries, it causes most hypothyroidism. However, iodine deficiency is the leading cause of hypothyroidism worldwide. Hashimoto thyroiditis is caused by antithyroid antibodies attacking thyroid tissue, creating fibrosis. The diagnosis might be difficult; hence the disease is occasionally identified late. Most lab tests show elevated thyroid-stimulating hormone (TSH), decreased thyroxine (T4), and enhanced antithyroid peroxidase (anti-TPO) antibodies. This exercise discusses Hashimoto thyroiditis' pathogenesis, diagnosis, and treatment, as well as the interprofessional team's role. Methodology: The study comprised 50 women with Hashimoto thyroditis, as well as a control group of 46 healthy, the patient and control who came to teaching Hospital between September 2022 and April 2023 in Basrah, Southern Iraq. TPA was measured using an Automated enzyme-linked fluorescence immunoassay (ELFA). Thyroid hormone (FT3, FT4, and TSH) was also measured using an Automated enzyme-linked fluorescence immunoassay (ELFA). Results; TPOA levels were significantly higher in patients compared to age-matched healthy controls, and FT4 and FT3 and levels were significantly lower in Hashimoto thyroiditis patients compared to age-matched healthy controls, according to the current study. Instead, and TSH are increased. Conclusions: From our results, we can conclude the relashinship between TPOA levels and Hashimoto thyroditis disease in women in Basra Governorate.