Publication Details
Abstract
This study aimed to evaluate the capability of the green tea leaf extract to decrease harmful effects on hormonal and histological changes in testicular tissue. The experiment was carried out on 24 Wister albino male rats, which divided into four groups (6 rats each group ) and treated as following: first group was received normal saline (0.9 NaCl) to serve as control, the second group was injected with gentamicin (100 mg/kg, i. p), the third group was injected with gentamicin at the same doses and treated with the extract of green tea (200 mg/kg), and the fourth group was received extract of green tea (200 mg/kg) only. The drug of induction and all the treatments were given for 10 days.
The results showed a significant decrease (p<0.05) in the level of testosterone in the gentamicin group compared with the control group and other groups. The group of green tea extract (200 mg/kg) and the (gentamicin +green tea 200 mg/kg) group did not show any significant difference (p<0.05) compared to the control group. The outcomes also demonstrated that using green tea extract reduced the histological damage caused by gentamycin to testicular tissue while raising testosterone levels.
In addition, the thickness of the interstitial tissue and the quantity of Leydig cells increased.
This suggests that green tea may have a function in tissue regeneration in addition to tissue repair, which could lead to several exciting applications for green tea in the protective effects of green tea extract on testis.