Prevalence of Periodontitis Among The Population: Findings From a Clinical Study

Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth, including the gingiva, periodontal ligament, and alveolar bone. The prevalence of this disease varies across different populations due to genetic, biological, and environmental factors. In Fergana, Uzbekistan, studying the distribution of periodontitis among various age groups and genders is crucial to understanding its epidemiology and risk factors. Periodontitis is not only a localized oral disease but also contributes to systemic conditions such as cardiovascular diseases, osteomyelitis, and sinusitis. The primary etiological agent, Porphyromonas gingivalis, plays a key role in the progression of periodontal destruction. Despite advancements in clinical treatments, early diagnosis and preventive strategies remain inadequate. The global burden of severe periodontitis ranks 11th among prevalent diseases, affecting 20–50% of the population. Addressing this issue requires innovative therapeutic approaches, including regenerative strategies using odontogenic stem cells and periodontal tissue engineering. Therefore, developing global therapeutic strategies is essential for periodontal tissue regeneration and effective disease management.