Publication Details
Abstract
Changes in the function of laboratory markers in the blood serum of the stomach were determined during the consumption of energy drinks at different periods of time.
This experimental study examines morphofunctional changes in the stomach wall.
The experiment was performed on 30 three-month-old white male rats weighing 130 ± 20 g. To obtain the experimental model, the energy drink (ED) "Gorilla" was administered intragastrically for 4, 8, 12 weeks through a plastic tube in the vivary department in Bukhara, during the period February 2022 - June2022.
The level of the tumor marker CA 74-2 varied from 0.2 to 4.02 U/ml in rats that received EN for 4 weeks. In blood samples from rats that consumed EN for 8 weeks, the tumor marker level varied from 1.36 to 5.38 U/ml, and when exposed to EN for 12 weeks, the tumor marker level varied from 2.1 to 24.15 U/ml. Only in 1 case (9%), in rats administered EN for 12 weeks, the tumor marker concentration increased to 24.15 U/ml.
When assessing the studied parameters that determine the functional state of the stomach in the blood serum, it was revealed that as a result of long-term action of EN, the secretory function of the stomach decreases and the risk of gastrointestinal diseases increases.