Publication Details
Abstract
Adenoid hypertrophy is one of the most common conditions affecting the upper respiratory tract in children and represents an important clinical and immunological problem in pediatric otorhinolaryngology. Enlargement of the adenoid tissue may lead to nasal obstruction, chronic inflammation, impaired respiratory function, and disturbances in immune regulation. The aim of this study was to evaluate the immunological changes associated with adenoid hypertrophy and their influence on respiratory function in children. A total of 120 children aged 4–12 years were included in the study, including 90 patients diagnosed with adenoid hypertrophy and 30 healthy children who formed the control group. Clinical examination, endoscopic evaluation, respiratory function assessment, and immunological laboratory analyses were performed. The results demonstrated that children with adenoid hypertrophy showed significant alterations in cytokine levels, increased inflammatory markers, and impaired respiratory parameters compared with the control group. These findings confirm that adenoid hypertrophy plays a significant role not only in mechanical airway obstruction but also in modulation of immune responses affecting respiratory health. The study highlights the importance of early diagnosis and immunological monitoring in children with adenoid hypertrophy.