Publication Details
Abstract
Background The postoperative shivering is a typical adverse effect of anesthesia. Shivering is among the most common causes of pain to post-surgery patients and unpleasant experience during and after spinal anesthesia. Thus, prevention and treatment of existing shivering can be considered as the clinically relevant intervention during the perioperative period.
Aim: To compare the safety and efficacy of nefopam and dexamethasone to prevent shivering in the case of cesarean section spinal anesthesia.
Method: 120 ASA II, III female patients who had undergone surgery using spinal anesthesia and a cesarean section were randomly selected into two groups, Group D with 60 pregnant women that were given the dose of dexamethasone (8 mg IV dexamethasone diluted in 100 ml normal saline) as infusion 15 minutes prior to administering spinal Group N, 60 pregnant women were treated with nefopam (20 mg IV nefopam in 100 ml normal saline) and the infusion of 15 minutes pre-induction of spinal anesthesia was performed. In both groups, in case of intraoperative shivering 25-50mg of pethidine IV bolus was administered as therapeutic intervention. Side effects were noted and incidence of shivering.
Results : The overall incidence of shivering was significant in D group compared to the N group (61.6% compared to 15, P>0.001) and that nefopam significantly decreased incidence of shivering.
Conclusion: prophylaxis nefopam (20mg) infusion was effective to reduce the rate of shivering during spinal anesthesia.