Publication Details
Abstract
Background: Spontaneous preterm birth (sPTB) causes infant morbidity and mortality. The preterm birth (Less than 37 weeks of gestation) takes place in 10%-12% of all births in the USA and is a severe health issue both to the mother and the child.
Aim: The objective of the present research was to relate the degree of lipid profile and spontaneous preterm births.
Methods: it is a case control study that will be carried out in obstetrics and gynecology department in Maternity and Pediatric teaching hospital, at Al Diwaniyah. The research was done between February 2024 and December 2024. a total of 60 pregnant women between the ages of 18-40 years were enrolled in the research. Women were divided into (30) cases of spontaneous preterm birth and (30) cases of spontaneous term birth which were referred to childbirth at labor room.
Result: The difference between the studied groups was statistically significant as concerned age, body mass index, parity whereas statistically significant difference between the studied groups was concerned gestational age. The statistically significant difference was nonexistent between the case group and control group as far as the Total Cholesterol, Triglyceride, LDL-Cholesterol and HDL-Cholesterol among others were concerned but the statistically significant difference was present between the case group and the control group as far as the CRP levels were concerned.
Conclusion: This paper demonstrates that high levels of the mother serum CRP are closely linked to preterm birth and can be a useful biological marker of inflammation to predict the at-risk women. Also, it was observed that low educational level and rural living also happened to be the major socio-demographic risk factors. Although the changes in the lipid profile were not so dramatic, the HDL reduction in the case group may indicate the existence of a potential relationship between the metabolic and inflammatory processes in preterm labor. It is suggested that further large-scale research is required to confirm these results and to investigate the applicability of CRP as a predictive instrument in the normal obstetric practice.