Publication Details
Abstract
In Uzbekistan, as elsewhere in the world, various categories of hyperglycemia, as well as the associated metabolic syndrome (MS), are widespread. Targeted measures are being taken in our country to reduce the risk of chronic noncommunicable diseases (NCDs). These measures include the prevention, treatment, and management of both NCDs and their associated risk factors. Particular attention is paid to type 2 diabetes and comorbid conditions. Furthermore, the population health program prioritizes the prevention of diseases, early mortality, and disability. The Resolutions of the President of the Republic of Uzbekistan No. PP-38 “On additional measures to deepen reforms in the healthcare sector” dated January 22, 2024 and No. PP-4063 “On measures to prevent non-communicable diseases, support a healthy lifestyle and increase the level of physical activity of the population” dated December 18, 2018 are aimed at resolving these issues. Today, there are about 352.1 million people with impaired glucose tolerance (IGT) in the world. By 2045, the number of people with IGT aged 20-79 years is expected to increase to 587 million, which will be 8.3% of the adult population. Currently, much attention is paid to the study of latent diabetes mellitus. This concept is consonant with the term prediabetes. Prediabetes includes IGT and impaired fasting glycemia. In this condition, glycemia indicators are above normal, but have not yet reached the indicators of T2DM. It is known that prediabetes significantly increases the risk of developing not only diabetes mellitus, but also cardiovascular diseases from endothelial dysfunction to heart failure, which significantly worsens the patient's quality of life and prognosis. Patients with impaired glucose tolerance (IGT) traditionally belong to the high-risk group for developing type 2 diabetes mellitus (T2DM). Diagnosing early disorders of carbohydrate metabolism in patients with obesity and type 2 diabetes is strategically justified, since, given that hyperglycemia often has a mild clinical manifestation and can remain undiagnosed for a long time, preventive measures can delay or prevent the development of both diabetes itself and its complications.