Publication Details
Abstract
Cancer is a major cause of mortality globally, affecting humans and animals equally. Inspite of this relevant advances in cancer research, the underlying biology of cancer remains poorly comprehend. This research aimed to explore the similarities and differences in cancer biology between humans and animals. Cancer has long been regarded as a genetic disease, and various research have been conducted on its genetic basis. These paper provide strong evidence for the genetic basis of cancer, example the notion that cancer is a disease that ends from the accumulation of genetic alterations, mutations, and epigenetic changes in major genes that regulate cell growth, division, and replication. Depending on the effects of genetic alterations of key genes in cancer development, these genes are divided into oncogenes and tumor suppressors. Genetic models of cancer growth have given relevant insights into the genetic processes that determine cancer initiation, progression, metastasis, the response to therapy, and the development of drug resistance Our results indicate that while there are similarities in cancer pathology and genetics, there are also distinct differences in tumor growing, progression, and response to treatment. These findings have relevant impactation for the development of novel cancer therapies and highlights the need for further research into the comparative biology of cancer.