Perinatal Risk Factors in Newborns from Multiple Pregnancies Following in Vitro Fertilization

Multiple pregnancies remain one of the most challenging conditions in modern obstetrics because they are frequently associated with prematurity, neonatal adaptation disorders, and increased perinatal morbidity, while pregnancies achieved through in vitro fertilization may additionally carry risks related to maternal reproductive history and assisted conception procedures. The present study aimed to compare perinatal risk factors and early neonatal outcomes among newborns delivered from multiple pregnancies after IVF and naturally conceived multiple pregnancies. A comparative clinical analysis was performed using data obtained from 120 newborns divided into two groups according to the method of conception. The results demonstrated that newborns from IVF-associated pregnancies had lower gestational age, reduced birth weight, higher frequency of respiratory distress syndrome, and more frequent admission to neonatal intensive care units. Naturally conceived multiple pregnancies also demonstrated elevated neonatal risks, although complications were comparatively less severe. The findings highlight the necessity for intensified prenatal surveillance and specialized neonatal management in pregnancies following assisted reproductive technologies.